Idorsia's development compounds target a number of different diseases.

Resistant Hypertension

Resistant hypertension is defined as uncontrolled persisting high systemic blood pressure despite concurrent administration of three antihypertensive therapies of different pharmacological classes at maximal or optimal doses, including a diuretic.

Systemic lupus erythematosus

Systemic lupus erythematosus (SLE), the most common form of Lupus, is an autoimmune disease. In SLE, the body's immune system mistakenly attacks healthy tissue, which can affect the skin, joints, kidneys, brain, and other organs.


Insomnia is defined as a combination of both dissatisfaction with sleep and a significant negative impact on daytime functioning. Insomnia is, worldwide, the most commonly reported sleeping disorder.

Cerebral vasospasm associated with aSAH

Aneurysmal subarachnoid hemorrhage (aSAH) is a sudden life-threatening bleeding occurring in the subarachnoid space.In about half of aSAH patients, after a few days of improvement, a worsening of their condition may occur due to a cerebral vasospasm.

Fabry disease

Fabry disease is a rare inherited genetic disorder in which patients have a deficiency or dysfunction of an enzyme which is essential for breaking down a fatty waste products in the cells of the body.