We work continuously to improve and evolve our business so as to reduce our impact and go beyond regulatory requirements. This means managing and monitoring our environmental impacts, specifically in relation to energy consumption, emissions, waste, and water.

Our headquarters in Allschwil (Switzerland) is the focus of our environmental impact management, as it is by far our largest site, where the majority of our pharmaceutical research takes place.

We seek to reduce consumption as far as possible; for instance, at headquarters, accounting for 99.7% of our total energy consumption, we are transitioning to LED lighting wherever possible, so as to significantly reduce our electricity consumption for office and laboratory lighting.

Most of the energy is consumed in our laboratories and offices, followed by fuel for vehicles. Our electricity supply at headquarters is 100% renewable, obtained from hydropower, while our heating mainly stems from the woodchip burner, supplemented by heating oil and gas.

Read the 2025 Sustainability Report for more information and disclosures.

In 2025, Idorsia established a global target for Scope 1 and Scope 2 emissions, and we are committed to achieving net-zero emissions by 2050 across all locations. To translate this ambition into credible action, we initiated the development of a climate transition plan defining priority measures and a clear reduction pathway. Within the next few years, we plan to phase out refrigerants with high global warming potential (GWP) and increase the procurement of renewable electricity, and we are assessing opportunities to connect to district heating for our Allschwil site. Together, these measures are expected to reduce our greenhouse gas emissions (Scope 1 and 2) by around 50% by 2030 compared with our 2024 baseline.

We monitor our greenhouse gas emissions yearly, according to the GHG Protocol, using the operational control method. Our Scope 1 and 2 emissions – primarily resulting from the combustion of energy sources to generate heat – have decreased by 15% compared to 2024.  These reductions are mainly due to lower refrigerant leakage and the related decreased refill of refrigerants in 2025, as well as reduced energy consumption following a change in the operational controlled office and laboratory areas in Switzerland. With these reductions, we are on our pathway to meet the net-zero target.

More information on the 2025 performance can be found in the 2025 Sustainability Report.

Waste prevention and appropriate disposal are key to safeguarding the environment and conserving raw materials and energy reserves. We aim to limit the environmental impact of our company so as to help ensure a safe and healthy environment for future generations. Most of our waste comes from our headquarters in Switzerland, which is by far our largest operating location. Other significant operating locations consist of leased offices, where waste is primarily domestic.

Read the 2025 Sustainability Report for more information and disclosures.

At Idorsia, water is used for a variety of purposes, such as laboratory experimentation, drinking, facility cooling, cleaning, and maintenance operations. Water management is part of Idorsia’s environmental management system, which covers all significant operating locations. Although our business is not water intensive, we work to minimize the use of this precious resource.

We strictly adhere to all regulations concerning water quality and potential impacts on water resources. As chemical substances may have adverse effects on water quality, our laboratories have strict procedures to prevent hazardous chemicals from being disposed of via the sink and thus entering the water system. Furthermore, we remain compliant with the strict wastewater quality standards set by external regulators. This includes priority substances of concern, which are monitored internally and externally. The discharge limits set for such substances by external regulators are adhered to.

Read the 2025 Sustainability Report for more information and disclosures.