The Sustainability Report 2025 (published February 26, 2026) covers operations in all affiliates of Idorsia. Any deviations from this reporting framework are indicated on a case-by-case basis. Annual performance data relates to the Group’s financial year (from January 1 to December 31).

The content of our sustainability reporting is aligned with the results of our 2023 materiality analysis and has been prepared in accordance with the GRI 2021 Standards. This report also complies with the requirements specified in Articles 964j–964l of the Code of Obligations and the Ordinance on Due Diligence and Transparency in relation to Minerals and Metals from Conflict-Affected Areas and Child Labour. It also complies with the requirements specified in Article 964b of the Code of Obligations, including the specific provisions set forth in the Ordinance on Climate Disclosures.

Sustainability Report 2025

GRI content index

TCFD assessment

In 2024, we deepened the risk and opportunity assessment, established robust governance structures and processes, integrated climate risks into our strategic planning according to TCFD guidelines, and enhanced our risk management frameworks to better anticipate and mitigate these challenges. In 2025, we updated the assessment through a structured screening for additional relevant climate-related risks and opportunities, and by reviewing and confirming the impact and likelihood ratings for transition risks and opportunities. Ratings for physical risks and opportunities were not updated in 2025, as the underlying CMIP6-based climate scenario and impact data have not been updated.

We report in accordance with the TCFD recommendations, as required under the Ordinance on Climate Disclosures. The TCFD index indicates where to find the specific TCFD contents within the report.

The TCFD index can be found in the Sustainability Report 2025.